Sao Manuel is located in Sao Paulo city, Brazil at the -22.7311, -48.5706 coordinates. Distance from Sao Manuel to other cities. are listed below, click on the city name to find distance between. Distance from São Manuel to Guarulhos 224 km, to Campinas 156 km, to Sao Bernardo do Campo 231 km. The green marker indicates the location of São Manuel.