Rio Grande is located in Zacatecas city, Mexico at the 23.8265, -103.0303 coordinates. Distance from Rio Grande to other cities. are listed below, click on the city name to find distance between. Distance from Río Grande to Fresnillo 74 km, to Guadalupe 130 km, to Jerez de Garcia Salinas 131 km. The green marker indicates the location of Río Grande.